Invitrogen™ MVP Monoclonal Antibody (1032)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA513871

Catalog No. PIMA513871

Description

MA5-13871 targets Major Vault Protein in FACS, GS, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples. The MA5-13871 immunogen is proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Specifications

• Antigen: MVP
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Formulation: PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q14764, Q62667
• Gene Symbols: MVP
• Immunogen: Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.
• Quantity: 500 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Gel Shift, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Clone: 1032
• Conjugate: Unconjugated
• Gene: MVP
• Gene Alias: 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 64681, 9961
• Content And Storage: 4°C
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov