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Invitrogen™ MVP Monoclonal Antibody (8B12)
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Catalog No. PIMA549162
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Catalog No. Quantity
PIMA549162 100 μg
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Catalog No. PIMA549162 Supplier Invitrogen™ Supplier No. MA549162
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Description

Mouse Monoclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human A549 tissue, human U2OS whole cell, human HepG2 whole cell, human THP-1 whole cell, human Hela whole cell, human SW620 whole cellrat RH35 whole cellmouse RAW2467 whole cell. IHC: mouse intestine tissue, human colon cancer tissue, rat intestine tissue, human mammary cancer tissue, human Lung cancer tissue, human Lung cancer tissue. ICC/IF: A431 cell. Flow: A549 cell, A431 cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MVP
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 8B12
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene MVP
Gene Accession No. Q14764, Q62667, Q9EQK5
Gene Alias 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
Gene Symbols MVP
Host Species Mouse
Immunogen E.coli-derived human MVP recombinant protein (Position: A2-H259).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64681, 78388, 9961
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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