MVP Mouse anti-Human, Clone: SPM280, Abnova™

Mouse monoclonal antibody raised against native human MVP.

Supplier:  Abnova Corporation MAB13191

Catalog No. 89-934-638

Description

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts. [provided by RefSeq]

Specifications

• Antigen: MVP
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow Cytometry (0.5-1 ug/10⁶ cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Gene Alias: LRP/VAULT1
• Host Species: Mouse
• Purification Method: Protein A/G purification
• Regulatory Status: RUO
• Gene ID (Entrez): 9961
• Content And Storage: Store at 4°C.
• Isotype: IgG1 κ

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed)
• Clone: SPM280
• Description: Mouse monoclonal antibody raised against native human MVP.
• Formulation: In 10mM PBS (0.05% BSA, 0.05% sodium azide).
• Gene Symbols: MVP
• Immunogen: Native purified MVP from human breast cancer MCF-7 cells.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid