Invitrogen™ MVP Polyclonal Antibody

Catalog No.	Quantity
PIPA582011	100 μL

Catalog No. PIPA582011 Supplier Invitrogen™ Supplier No. PA582011

Description

Rabbit Polyclonal Antibody

Immunogen sequence: VFEEVLDLVD AVILTEKTAL HLRARRNFRD FRGVSRRTGE EWLVTVQDTE AHVPDVHEEV LGVVPITTLG PHNYCVILDP VGPDGKNQLG QKRVVKGEKS FFLQPGEQLE QGIQDVYVLS Highest antigen sequence indentity to the following orthologs: Rat - 91%, Mouse - 91%.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

Specifications

• Antigen: MVP
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene: MVP
• Gene Accession No.: Q14764
• Gene Alias: 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
• Gene Symbols: MVP
• Host Species: Rabbit
• Immunogen: Recombinant protein corresponding to Human MVP. Recombinant protein control fragment (Product #RP-101753).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9961
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG