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Invitrogen™ MVP Recombinant Rabbit Monoclonal Antibody (4S1H7)
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Catalog No. PIMA537828
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PIMA537828 100 μL
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Catalog No. PIMA537828 Supplier Invitrogen™ Supplier No. MA537828
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: HT-29, A-549, Mouse lung, Mouse liver, Rat lung, Rat kidney Immunogen sequence: MATEEFIIRI PPYHYIHVLD QNSNVSRVEV GPKTYIRQDN ERVLFAPMRM VTVPPRHYCT VANPVSRDAQ GLVLFDVTGQ VRLRHADLEI RLAQDPFPLY.

This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MVP
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 4S1H7
Concentration 0.35 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MVP
Gene Accession No. Q14764, Q62667, Q9EQK5
Gene Alias 2310009M24Rik; LRP; Lung resistance-related protein; major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP
Gene Symbols MVP
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MVP (Q14764).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64681, 78388, 9961
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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