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Invitrogen™ MX2 Polyclonal Antibody
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Catalog No. PIPA536985
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100 μL
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PIPA536985 100 μL
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Catalog No. PIPA536985 Supplier Invitrogen™ Supplier No. PA536985
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 82 kDa. Purity is >95% by SDS-PAGE.

Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MX2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene MX2
Gene Accession No. P20592
Gene Alias AI528743; interferon-induced GTP-binding protein Mx2; interferon-induced GTP-binding protein Mx3; interferon-regulated resistance GTP-binding protein MXB; MX dynamin like GTPase 2; MX dynamin-like GTPase 2; Mx2; Mx-2; Mx3; MXB; myxovirus (influenza virus) resistance 2; myxovirus (influenza virus) resistance 3; myxovirus resistance protein 2; myxovirus resistance protein 3; p78-related protein; protein MxB; second interferon-induced protein p78
Gene Symbols MX2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 414-459 of human MX2.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4600
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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