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Invitrogen™ MX2 Polyclonal Antibody
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Catalog No. PIPA5102005
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100 μL
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PIPA5102005 100 μL
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Catalog No. PIPA5102005 Supplier Invitrogen™ Supplier No. PA5102005
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MX2.

Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MX2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MX2
Gene Accession No. P20592, Q9WVP9
Gene Alias AI528743; interferon-induced GTP-binding protein Mx2; interferon-induced GTP-binding protein Mx3; interferon-regulated resistance GTP-binding protein MXB; MX dynamin like GTPase 2; MX dynamin-like GTPase 2; Mx2; Mx-2; Mx3; MXB; myxovirus (influenza virus) resistance 2; myxovirus (influenza virus) resistance 3; myxovirus resistance protein 2; myxovirus resistance protein 3; p78-related protein; protein MxB; second interferon-induced protein p78
Gene Symbols MX2
Host Species Rabbit
Immunogen A synthesized peptide derived from human MX2(Accession P20592), corresponding to amino acid residues E372-L422.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17858, 4600
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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