Invitrogen™ MX2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102005

Catalog No. PIPA5102005

Description

Antibody detects endogenous levels of total MX2.

Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.

Specifications

• Antigen: MX2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MX2
• Gene Alias: AI528743; interferon-induced GTP-binding protein Mx2; interferon-induced GTP-binding protein Mx3; interferon-regulated resistance GTP-binding protein MXB; MX dynamin like GTPase 2; MX dynamin-like GTPase 2; Mx2; Mx-2; Mx3; MXB; myxovirus (influenza virus) resistance 2; myxovirus (influenza virus) resistance 3; myxovirus resistance protein 2; myxovirus resistance protein 3; p78-related protein; protein MxB; second interferon-induced protein p78
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17858, 4600
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P20592, Q9WVP9
• Gene Symbols: MX2
• Immunogen: A synthesized peptide derived from human MX2(Accession P20592), corresponding to amino acid residues E372-L422.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG