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Invitrogen™ MYBBP1A Polyclonal Antibody
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Catalog No. PIPA568828
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100 μL
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PIPA568828 100 μL
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Catalog No. PIPA568828 Supplier Invitrogen™ Supplier No. PA568828
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Guinea Pig: 83%; Mouse: 100%; Rat: 92%.

The Myb family of transcription factors, which includes the structurally related A-, B-, and c-Myb genes, regulate differentiation, cellular growth and transactivating gene expression. c-Myb plays an essential role in controlling the proliferation and differentiation of hematopoietic cells, cellular levels of c-Myb decreasing as cells reach terminal differentiation. Myb-binding protein 1A (MYBBP1A) is a novel nuclear protein localized predominantly, but not exclusively, in nucleoli. Although initially isolated as a c-Myb-interacting protein, MYBBP1A is expressed ubiquitously, and associates with a number of different transcription factors. MYBBP1A associates with the aromatic hydrocarbon receptor (AhR), enhancing transactivation and increasing AhR-dependent gene expression. MYBBP1A is a powerful negative regulator of PPAR gamma coactivator 1 alpha (PGC-1 alpha) by p38 MAPK and also acts as a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYBBP1A
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene MYBBP1A
Gene Accession No. Q7TPV4
Gene Alias AL024407; AU019902; DBP; MYB binding protein 1a; MYB binding protein (P160) 1a; MYB binding protein 1a; myb-binding protein 1A; Myb-binding protein of 160 kDa; MYBBP1A; nuclear protein P160; P160; p160MBP; p53-activated protein-2; p67MBP; PAP2; PAR interacting protein; PAR-interacting protein; PIP
Gene Symbols MYBBP1A
Host Species Rabbit
Immunogen synthetic peptide directed towards the C terminal region of mouse MYBBP1A.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18432
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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