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Invitrogen™ MYBBP1A Polyclonal Antibody
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Catalog No. PIPA585666
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100 μL
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PIPA585666 100 μL
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Catalog No. PIPA585666 Supplier Invitrogen™ Supplier No. PA585666
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Positive Control: Jurkat, Raji, NCI-H929, 293T. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Myb family of transcription factors, which includes the structurally related A-, B-, and c-Myb genes, regulate differentiation, cellular growth and transactivating gene expression. c-Myb plays an essential role in controlling the proliferation and differentiation of hematopoietic cells, cellular levels of c-Myb decreasing as cells reach terminal differentiation. Myb-binding protein 1A (MYBBP1A) is a novel nuclear protein localized predominantly, but not exclusively, in nucleoli. Although initially isolated as a c-Myb-interacting protein, MYBBP1A is expressed ubiquitously, and associates with a number of different transcription factors. MYBBP1A associates with the aromatic hydrocarbon receptor (AhR), enhancing transactivation and increasing AhR-dependent gene expression. MYBBP1A is a powerful negative regulator of PPAR gamma coactivator 1 alpha (PGC-1 alpha) by p38 MAPK and also acts as a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYBBP1A
Applications Western Blot
Classification Polyclonal
Concentration 0.52 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene MYBBP1A
Gene Accession No. Q9BQG0
Gene Alias AL024407; AU019902; DBP; MYB binding protein 1a; MYB binding protein (P160) 1a; MYB binding protein 1a; myb-binding protein 1A; Myb-binding protein of 160 kDa; MYBBP1A; nuclear protein P160; P160; p160MBP; p53-activated protein-2; p67MBP; PAP2; PAR interacting protein; PAR-interacting protein; PIP
Gene Symbols MYBBP1A
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human MYBBP1A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10514
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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