Invitrogen™ MYBBP1A Recombinant Rabbit Monoclonal Antibody (JB40-09)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA534702

Catalog No. PIMA534702

Description

Positive Control: A549.

The Myb family of transcription factors, which includes the structurally related A-, B-, and c-Myb genes, regulate differentiation, cellular growth and transactivating gene expression. c-Myb plays an essential role in controlling the proliferation and differentiation of hematopoietic cells, cellular levels of c-Myb decreasing as cells reach terminal differentiation. Myb-binding protein 1A (MYBBP1A) is a novel nuclear protein localized predominantly, but not exclusively, in nucleoli. Although initially isolated as a c-Myb-interacting protein, MYBBP1A is expressed ubiquitously, and associates with a number of different transcription factors. MYBBP1A associates with the aromatic hydrocarbon receptor (AhR), enhancing transactivation and increasing AhR-dependent gene expression. MYBBP1A is a powerful negative regulator of PPAR gamma coactivator 1 alpha (PGC-1 alpha) by p38 MAPK and also acts as a nucleocytoplasmic shuttling protein that utilizes CRM1-dependent and independent nuclear export pathways.

Specifications

• Antigen: MYBBP1A
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q9BQG0
• Gene Symbols: MYBBP1A
• Immunogen: Synthetic peptide within Human MYBBP1A aa 1,051-1,100.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry
• Clone: JB40-09
• Conjugate: Unconjugated
• Gene: MYBBP1A
• Gene Alias: AL024407; AU019902; DBP; MYB binding protein 1a; MYB binding protein (P160) 1a; MYB binding protein 1a; myb-binding protein 1A; Myb-binding protein of 160 kDa; MYBBP1A; nuclear protein P160; P160; p160MBP; p53-activated protein-2; p67MBP; PAP2; PAR interacting protein; PAR-interacting protein; PIP
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 10514
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles, store in dark
• Form: Liquid