Invitrogen™ MYBPC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5115605

Catalog No. PIPA5115605

Description

Antibody detects endogenous levels of total MYBPC3.

Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.

Specifications

• Antigen: MYBPC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYBPC3
• Gene Alias: cardiac C-protein; cardiac MyBP-C; cardiac myosin binding protein C; CMD1MM; CMH4; C-protein, cardiac muscle isoform; DKFZp779E1762; FHC; LVNC10; MYBP-C; Mybpc3; myosin binding protein C, cardiac; myosin binding protein C3; myosin-binding protein C, cardiac-type; truncated cardiac myosin-binding protein C
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4607
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q14896
• Gene Symbols: MYBPC3
• Immunogen: A synthesized peptide derived from human MYBPC3(Accession Q14896), corresponding to amino acid residues A1198-G1248.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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