Invitrogen™ MYBPC3 Polyclonal Antibody

Catalog No.	Quantity
PIPA547925	100 μg

Catalog No. PIPA547925 Supplier Invitrogen™ Supplier No. PA547925

Description

Sheep Polyclonal Antibody

In direct ELISAs, approximately 25% cross-reactivity with recombinant mouse MyBPC3 is observed. Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.

Specifications

• Antigen: MYBPC3
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 5% trehalose and No Preservative
• Gene: MYBPC3
• Gene Accession No.: Q14896
• Gene Alias: cardiac C-protein; cardiac MyBP-C; cardiac myosin binding protein C; CMD1MM; CMH4; C-protein, cardiac muscle isoform; DKFZp779E1762; FHC; LVNC10; MYBP-C; Mybpc3; myosin binding protein C, cardiac; myosin binding protein C3; myosin-binding protein C, cardiac-type; truncated cardiac myosin-binding protein C
• Gene Symbols: MYBPC3
• Host Species: Sheep
• Immunogen: E. coli-derived recombinant human MyBPC3 Arg1001-Lys1103.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 4607
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG

Safety and Handling

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