MYBPC3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 199771AP
The antibody detects the full length form and the degradation bands around 28-54 kDa in SDS-PAGE.MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O70468, P56741, Q14896|
|Cardiac MyBP C, CMH4, FHC, MYBP C, MYBPC3|
|17868, 295929, 4607|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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