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Myc Tag Mouse anti-Human, Clone: 9E10, Bioss
SDP

Catalog No. 501979801
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50-197-9801 100 μL
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Catalog No. 50-197-9801 Supplier Bioss Supplier No. BSM51003M
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Mouse Monoclonal Antibody

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

Specifications

Antigen Myc Tag
Applications Western Blot
Classification Monoclonal
Clone 9E10
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene MYC
Gene Accession No. P01106
Gene Alias 46-0603; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; MYCC; myc-related translation/localization regulatory factor; Proto-oncogene c-Myc; R95025; R950-25; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols MYC
Host Species Mouse
Immunogen KLH conjugated synthetic peptide encoding c-Myc tag (AEEQKLISEEDLLRKRREQLKHKLE) was used as antigen.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4609
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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