MYCN Monoclonal Antibody (OTI2D5), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA809343

Catalog No. 50-168-2727

Description

N-Myc protein is member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in the context of various cellular growth and differentiation processes. MYCN gene is considered the hallmark of neuroblastoma, amplification and overexpression of the MYCN proto-oncogene occurs in approximately 20% of neuroblastomas and is associated with advanced stage disease, rapid tumor progression, and poor prognosis.

Specifications

• Antigen: MYCN
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P04198
• Gene Symbols: MYCN
• Immunogen: Human recombit protein fragment corresponding to amino acids 229-464 of human MYCN produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI2D5
• Conjugate: Unconjugated
• Gene: MYCN
• Gene Alias: MODED, N-myc, NMYC, ODED, bHLHe37
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4613
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid