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Invitrogen™ Mycobacterium tuberculosis Tb10.3 Polyclonal Antibody
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Catalog No. PIPA5122318
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100 μg
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PIPA5122318 100 μg
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Catalog No. PIPA5122318 Supplier Invitrogen™ Supplier No. PA5122318
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Description

Rabbit Polyclonal Antibody

This antibody reacts with Mycobacterium tuberculosis protein Tb10.3 (EsxR).

The gene encoding TB10.3 was found to belong to a subfamily within the esat-6 family that consists of the three highly homologous proteins TB10.4, TB10.3, and TB12.9 (Rv0288, Rv3019c, and Rv3017c, respectively). Southern blot analysis combined with database searches revealed that the three members of the TB10.4 family were present only in strains of the Mycobacterium tuberculosis complex, including BCG, and M. kansasii, whereas other atypical mycobacteria had either one (M. avium, M. intracellulare, and M. marinum) or none (M. scrofulaceum, M. fortuitum, and M. szulgai) of the genes. The fine specificity of the T-cell response to the three closely related esat-6 family members was markedly different, with only a few epitopes shared between the molecules. (PubMed: 12228269).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Mycobacterium tuberculosis Tb10.3
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 15mM sodium azide; pH 7.4
Gene esxR
Gene Accession No. P9WNI9
Gene Symbols esxR
Host Species Rabbit
Immunogen Recombinant Tb10.3 protein (produced in E. coli).
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 888926
Target Species Bacteria
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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