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Invitrogen™ MYCT1 Polyclonal Antibody
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Catalog No. PIPA524018
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400 μL
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Catalog No. Quantity
PIPA524018 400 μL
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Catalog No. PIPA524018 Supplier Invitrogen™ Supplier No. PA524018
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Description

Rabbit Polyclonal Antibody

MYCT1 Polyclonal Antibody for Western Blot, Flow

MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYCT1
Applications Flow Cytometry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene Myct1
Gene Accession No. Q8N699
Gene Alias 1110020B04Rik; AI225941; AI642973; MTLC; MTMC1; MT-MC1; myc target 1; myc target in myeloid cells 1; myc target in myeloid cells protein 1; Myc target protein 1; Myct1
Gene Symbols Myct1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 135-163 amino acids from the C-terminal region of human MYCT1.
Purification Method Antigen Affinity Chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 80177
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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