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Invitrogen™ MYCT1 Polyclonal Antibody
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Catalog No. PIPA534450
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100 μg
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Catalog No. Quantity
PIPA534450 100 μg
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Catalog No. PIPA534450 Supplier Invitrogen™ Supplier No. PA534450
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Rabbit Polyclonal Antibody

A suggested positive control is rat lung tissue lysate. PA5-34450 can be used with blocking peptide PEP-1492.

MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYCT1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Myct1
Gene Accession No. Q8N699, Q8R411
Gene Alias 1110020B04Rik; AI225941; AI642973; MTLC; MTMC1; MT-MC1; myc target 1; myc target in myeloid cells 1; myc target in myeloid cells protein 1; Myc target protein 1; Myct1
Gene Symbols Myct1
Host Species Rabbit
Immunogen A 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 292264, 68632, 80177
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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