Invitrogen™ Myelin Monoclonal Antibody (2B5)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135712

Catalog No. 01-672-018

Description

In paraffin sections antibody pm 43 recognizes only myelin in the peripheral nervous system (PNS). In frozen sections it also reacts with myelin in the central nervous system (CNS). Is useful for studying myelination and demyelination processes in the PNS, and remyelination processes in the CNS as can be observed after trauma in multiple sclerosis. Reacts with a 43 kD protein in immunoblotting. Positive control: Peripheral nerve.

Myelin is a membrane characteristic of the nervous tissue and functions as an insulator to increase the velocity of the stimuli being transmitted between a nerve cell body and its target. Myelin isolated from human and bovine nervous tissue is composed of approximately 80% lipid and 20% protein, and 30% of the protein fraction constitutes myelin basic protein.

Specifications

• Antigen: Myelin
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Ascites with 0.09% sodium azide
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: 2B5
• Conjugate: Unconjugated
• Gene Alias: BTN6; BTNL11; MGC99675; MOG; MOG alpha-5; MOG AluA; MOG AluB; MOG Ig-AluB; MOGIG2; myelin oligodendrocyte glycoprotein; myelin-oligodendrocyte glycoprotein; NRCLP7
• Immunogen: Human myelin isolated from peripheral nervous system.
• Regulatory Status: RUO
• Target Species: Human, Mammalia, Mouse, Rat
• Product Type: Antibody
• Isotype: IgM