Invitrogen™ Myeloperoxidase Monoclonal Antibody (4A4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA120074

Catalog No. PIMA120074

Description

MA1-20074 detects Myeloperoxidase in human samples.

Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.

Specifications

• Antigen: Myeloperoxidase
• Classification: Monoclonal
• Concentration: 4.6 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P05164
• Gene Symbols: MPO
• Immunogen: Purified, full length, native, human myeloperoxidase protein.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Affinity Purification, ELISA, Western Blot
• Clone: 4A4
• Conjugate: Unconjugated
• Gene: MPO
• Gene Alias: 84 kDa myeloperoxidase; 89 kDa myeloperoxidase; mKIAA4033; MPO; Myeloperoxidase; Myeloperoxidase heavy chain; Myeloperoxidase light chain
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 4353
• Content And Storage: 4°C, do not freeze
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov