Invitrogen™ MYF5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579715

Catalog No. PIPA579715

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human SW620 cell, mouse testis tissue.

Myogenic factor 5 (MYF5) is a gene located on chromosome 12q21.31, encoding a basic helix-loop-helix (bHLH) transcription factor essential for skeletal muscle development and differentiation. MYF5 is one of the key members of the myogenic regulatory factor (MRF) family, which also includes MyoD, myogenin, and MRF4. It plays a crucial role in myogenesis by regulating the expression of genes necessary for muscle precursor cell proliferation and differentiation into mature muscle fibers. During embryonic development, MYF5 is involved in the formation of muscle tissue and maintenance of muscle progenitor cells. Mutations or dysregulation in MYF5 can lead to developmental abnormalities in muscle formation and are implicated in muscle-related disorders. Research into MYF5 continues to explore its regulatory mechanisms in muscle biology and potential therapeutic applications in muscular dystrophies and muscle repair processes.

Specifications

• Antigen: MYF5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYF5
• Gene Alias: B130010J22Rik; basic helix-loop-helix nuclear protein; bHLHc2; cb641; Class C basic helix-loop-helix protein 2; muscle regulatory protein Myf5; MYF5; myf-5; myf5 protein; MyoD family; myogenic factor 5; myogenic factor-5; myogenic regulatory factor 5; myogenic regulatory factor MYF-5; unnamed protein product; zgc:110509
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17877, 299766, 4617
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and 0.05mg sodium azide
• Gene Accession No.: P13349, P24699
• Gene Symbols: MYF5
• Immunogen: E. coli-derived human Myf5 recombinant protein (Position: E25-Y146).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG