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MYH7 Monoclonal Antibody (TH81 (BGN/04/4481)), Invitrogen™

Catalog No. PIMA183347
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200 μg
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Catalog No. Quantity
PIMA183347 200 μg
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Catalog No. PIMA183347 Supplier Thermo Scientific Supplier No. MA183347

Description

Mouse Monoclonal Antibody

Mouse anti Rabbit muscle myosin heavy chain antibody, clone TH81 recognizesthe heavy chain of rabbit muscle myosin.

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYH7
Applications ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone TH81 (BGN/04/4481)
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with <0.1% sodium azide; pH 7.2
Gene Myh7
Gene Accession No. P02564, P04461, P12883, Q91Z83
Gene Alias beta cardiac myosin heavy chain; beta myosin heavy chain; beta-MHC; beta-myosin; beta-myosin heavy chain; beta-myosin-heavy-chain; B-MHC; cardiac muscle myosin heavy chain 7 beta; cardiac myosin heavy chain beta isoform; CMD1S; CMH1; LOC100727138; mg:cb02g011; MPD1; Myh7; MYH-beta/slow; MyHC-alpha; Myhcb; Myhc-b; myHC-beta; MyHC-I; MyHC-slow; myopathy, distal 1; myosin beta heavy chain; myosin heavy chain 1; myosin heavy chain 7; myosin heavy chain cardiac alpha; myosin heavy chain polypeptide 7 cardiac muscle fetal; myosin heavy chain slow; myosin heavy chain slow isoform; myosin heavy chain slow type 1 (beta cardiac); myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 7; myosin, heavy chain 7, cardiac muscle, beta; myosin, heavy polypeptide 7, cardiac muscle, beta; myosin-7; rhabdomyosarcoma antigen MU-RMS-40.7A; slow myosin heavy chain; smyhc3; SPMD; SPMM; type slow/beta myosin heavy chain; Unknown (protein for IMAGE:7985957); ventricular myosin heavy chain; vmhc
Gene Symbols Myh7
Host Species Mouse
Immunogen Myosin heavy chain from rabbit muscle.
Purification Method Protein G
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100101566, 140781, 29557, 4625
Target Species Human, Mouse, Rabbit, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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