MYH7 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-607-761	150 μL

Catalog No. 50-607-761 Supplier Proteintech Group Inc Supplier No. 222801AP150UL

Description

Rabbit Polyclonal Antibody

This antibody can specifically recognize endogenous MYH7, not cross-reacting with other MHCs.

Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predomitly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.

Specifications

• Antigen: MYH7
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.66 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: MYH7
• Gene Accession No.: P12883, Q91Z83
• Gene Alias: beta MHC, CMD1S, CMH1, MPD1, MYH7, MyHC beta, MyHC slow, MYHCB, Myosin 7, Myosin heavy chain 7, SPMD, SPMM
• Gene Symbols: MYH7
• Host Species: Rabbit
• Immunogen: Peptide
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 140781, 4625
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG