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Invitrogen™ MYH8 Polyclonal Antibody
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Catalog No. PIPA5103936
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PIPA5103936 100 μL
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Catalog No. PIPA5103936 Supplier Invitrogen™ Supplier No. PA5103936
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MYH8.

Myosin is a highly conserved, ubiquitously expressed protein that interacts with Actin to generate the force for cellular movements. Conventional Myosins are hexameric proteins consisting of two heavy chain subunits, a pair of non-phosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of Myosin have been cloned: smooth muscle Myosins, striated muscle Myosins and non-muscle Myosins. Contractile activity in smooth muscle is regulated by the calcium/calmodulin-dependent phosphorylation of Myosin light chain (MLC) by Myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of Myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYH8
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MYH8
Gene Accession No. P13535
Gene Alias 4832426G23Rik; AI327267; Beta-MHC antisense; DA7; fetal-myosin heavy chain; gtMHC-F; MHCp; Myh8; MyHC-peri; MyHC-perinatal; MyHC-pn; Myhsp; Myhs-p; Myosin 8; Myosin heavy chain 8; myosin heavy chain, skeletal muscle, perinatal; myosin, heavy chain 8, skeletal muscle, perinatal; myosin, heavy polypeptide 8, skeletal muscle, perinatal; Myosin8; myosin-8
Gene Symbols MYH8
Host Species Rabbit
Immunogen A synthesized peptide derived from human MYH8(Accession P13535), corresponding to amino acid residues D1211-E1261.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4626
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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