MYL7 Monoclonal Antibody (OTI3A8), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA800218

Catalog No. 50-167-8181

Description

Encoded by the MYL7 gene, myosin regulatory light chain 7, also designated Myosin regulatory light chain 2, atrial isoform (MLC-2a), is part of a hexameric complex of two heavy chains and four light chains predomitly expressed in adult atrial muscle. Myosin regulatory light chain 7 binds calcium and has been shown to be a useful molecular marker for cardiac chamber specification. The co-expression of myosin regulatory light chain 7 and myosin light chain 2 (MLC2v) in the outflow tract and atrioventricular canal, together with the single expression in the atrial (MYL7) and ventricular (MYL2) myo-cardium, permits the delineation of their boundaries. At the amino acid level there is 95% homology between the human and mouse myosin regulatory light chain 7 sequences.

Specifications

• Antigen: MYL7
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q01449
• Gene Symbols: MYL7
• Immunogen: Full length human recombit protein of human MYL7 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI3A8
• Conjugate: Unconjugated
• Gene: MYL7
• Gene Alias: MYL2A, MYLC2A
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 58498
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid