Invitrogen™ MYL9/MRLC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA599657

Catalog No. PIPA599657

Description

Antibody detects endogenous levels of total MRLC1/MRLC2.

Myosin regulatory light polypeptide 9 is a highly conserved, ubiquitously expressed protein that in humans is encoded by the MYL9 gene. Myosin, a structural component of muscle, are hexameric proteins consisting of two heavy chains and four light chains, including a single pair of nonphosphorylatable light chain subunits and another pair of phosphorylatable light chain subunits.The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. Myosin light chain (Myl) 9 and Myl12 are new functional ligands for CD69. Blockade of CD69-Myl9/12 interactio ameliorates allergic airway inflammation in ovalbumin-induced and house dust mite-induced mouse models of asthma.

Specifications

• Antigen: MYL9/MRLC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYL12A
• Gene Alias: 1500001M02Rik; 20 kDa myosin light chain; 2900073G15Rik; AI327049; AI838292; brain specific myosin regulatory light chain; C77744; C80200; Epididymis secretory protein Li 24; HEL-S-24; LC20; MLC2; MLC-2; MLC20; MLC-2A; MLC-2B; MLC-2C; MLCB; MLC-B; MRCL3; MRLC1; Mrlc2; MRLC3; Mrlcb; Myl12a; MYL12B; MYL2B; MYL9; MYLC2B; Mylc2c; myosin light chain 12A; myosin light chain 12B; myosin light chain 9; myosin light chain, regulatory B; myosin light chain, regulatory B-like; myosin light chain, regulatory C; myosin regulatory light chain 1; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; myosin regulatory light chain 2; myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 2, smooth muscle isoform; myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; myosin regulatory light chain-B; myosin regulatory light polypeptide 9; Myosin RLC; myosin RLC-A; Myosin RLC-B; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light chain 12B, regulatory; myosin, light chain 9, regulatory; myosin, light polypeptide 9, regulatory; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); MYRL2; NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; RLC-B; RLC-C; SHUJUN-1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 103910, 10398, 10627, 296313, 501203, 50685, 67268, 67938, 98932
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O14950, P13832, P18666, P19105, P24844, Q3THE2, Q64122, Q9CQ19
• Gene Symbols: MYL12A, MYL12B, MYL9
• Immunogen: A synthesized peptide derived from human MYL9(Accession P24844), corresponding to amino acid residues M1-Q43.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG