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MYO18A Polyclonal Antibody, Invitrogen™

Catalog No. PIPA554328
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PIPA554328 100 μL
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Catalog No. PIPA554328 Supplier Thermo Scientific Supplier No. PA554328

Description

Rabbit Polyclonal Antibody

Immunogen sequence: RFSFSQRSRD ESASETSTPS EHSAAPSPQV EVRTLEGQLV QHPGPGIPRP GHRSRAPELV TKKFPVDLRL PPVVPLPPPT LRELELQRRP TGDFGFSLRR TTMLDRGPEG QACRRVVHFA EP Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 89%.

MYO18A may link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. May be involved in the maintenance of the stromal cell architectures required for cell to cell contact. Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYO18A
Applications Immunohistochemistry
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MYO18A
Gene Accession No. Q92614
Gene Alias CD245; KIAA0216; MAJN; molecule associated with JAK3 N-terminus; Myo18a; MyoPDZ; myosin 18a; myosin containing a PDZ domain; myosin containing PDZ domain; myosin XVIIIa; myosin XVIIIb; myosin-XVIIIa; MysPDZ; SP-A receptor subunit SP-R210 alphaS; SPR210; SP-R210; Surfactant protein receptor SP-R210; Unconventional myosin-XVIIIa
Gene Symbols MYO18A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MYO18A
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 399687
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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