Invitrogen™ MYO1C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593297

Catalog No. PIPA593297

Description

Immunogen sequence: ENAFFLDHVR TSFLLNLRRQ LPQNVLDTSW PTPPPALREA SELLRELCIK NMVWKYCRSI SPEWKQQLQQ KAVASEIFKG KKDNYPQSVP RLFISTRLGT DEISPRVLQA LGSEPIQYAV PVVKYDRKGY KPRSRQLLLT PNAVVIVEDA KVKQRIDYAN LTGISVSSLS DSLFVLHVQR ADNKQKGDVV LQSDHVIETL TKTALSANRV NSININQGSI TFAGGPGRDG TIDFTPGSEL LITKAKNGHL AVVAPRLNSR; Positive Samples: HT-29, SKOV3, Mouse lung, Rat lung; Cellular Location: Cell membrane, Cell projection, Cytoplasm, Cytoplasmic side, Cytoplasmic vesicle, Nucleus, Nucleus, Peripheral membrane protein, nuclear pore complex, nucleolus, nucleoplasm, ruffle, stereocilium membrane.

MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.

Specifications

• Antigen: MYO1C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYO1C
• Gene Alias: C80397; FLJ23903; mm1beta; MMIb; MMI-beta; myo1c; myo1ca; MYO1E; myosin 1c, paralog a; myosin heavy chain myr 2; myosin I; Myosin I beta; myosin IB; myosin IC; myosin Ic, paralog a; myosin IC-like; myosin-I beta; myosin-Ibeta; myosin-Ic; Myr2; NMI; nuclear myosin I; nuclear myosin I beta; si:ch211-69i14.4; unconventional myosin Myr2 I heavy chain; unconventional myosin-Ic
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 17913, 4641, 65261
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Concentration: 0.95 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00159, Q63355, Q9WTI7
• Gene Symbols: MYO1C
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_2036933).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG