Invitrogen™ MYO3A Monoclonal Antibody (8D12)

Catalog No.	Quantity
PIMA524580	50 μg

Catalog No. PIMA524580 Supplier Invitrogen™ Supplier No. MA524580

Description

Mouse Monoclonal Antibody

Peptide Sequence: HEEINNIKKK DNKDSKATSE REACGLAIFS KQISKLSEEY FILQKKLNEM ILSQQLKSLY LGVSHHKPIN RRVSSQQCLS GVCKGEEPKI L.

MYO3A (MYO3 alpha) serine/threonine kinase belongs to the myosin superfamily where they are categorized into conventional myosins (class II) and unconventional myosins (classes I and III through XV) based on their variable C-terminal cargo-binding domains. Class III myosins, such as MYO3A, have a kinase domain N-terminal to the conserved N-terminal motor domains and are expressed in photoreceptors. MYO3A plays an important role in hearing in humans and mutations in the MYO3A have been shown to cause nonsyndromic progressive hearing loss. MYO3A is highly expressed in retina and cochlea.

Specifications

• Antigen: MYO3A
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: 8D12
• Concentration: 0.39 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with no preservative; pH 7.4
• Gene: MYO3A
• Gene Accession No.: Q8NEV4
• Gene Alias: DFNB30; MYO3A; myosin IIIA; myosin-IIIa
• Gene Symbols: MYO3A
• Host Species: Mouse
• Immunogen: MYO3A (NP_059129, 1400 a.a. ~ 1490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Purification Method: Protein A
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 53904
• Target Species: Human
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG2b κ