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Invitrogen™ MYO7A Polyclonal Antibody
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Catalog No. PIPA537182
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100 μL
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PIPA537182 100 μL
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Catalog No. PIPA537182 Supplier Invitrogen™ Supplier No. PA537182
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 254 kDa. Purity is >95% by SDS-PAGE.

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYO7A
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene MYO7A
Gene Accession No. Q13402
Gene Alias DFNA11; DFNB2; Hdb; motor protein; MyO VIIa; Myo7; Myo7a; myosin; myosin 7a; myosin VIIA; myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)); myosin-VIIa; Myosin-VIIa motor domain; MYOVIIA; MYU7A; nmf371; NSRD2; polka; sh1; sh-1; shaker 1; unconventional myosin-VIIa; USH1B
Gene Symbols MYO7A
Host Species Rabbit
Immunogen A synthetic peptide corresponding to residues in human Myosin VIIa.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4647
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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