Invitrogen™ MYO7A Recombinant Rabbit Monoclonal Antibody (31A12)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA550108

Catalog No. FEMA550108

Description

MYO7A Recombinant Monoclonal Antibody for Flow, ELISA

Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins. Defects in the myosin VIIa gene are responsible for hearing impairment in shaker-1 (sh1) mice and causes Usher syndrome IB in humans. Usher syndrome associates congenital deafness, vestibular dysfunction, and retinitis pigmentosa and is the most common form of combined deafness and blindness. Structural features of myosin VIIa protein include an ATP binding N-terminal motor domain, a central region which possess five light-chain binding (IQ) motifs, and a C-terminal domain with three myosin tail homology (MyTH4) and talin-like homology regions.

Specifications

• Antigen: MYO7A
• Classification: Recombinant Monoclonal
• Concentration: 2 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13402
• Gene Symbols: MYO7A
• Immunogen: A synthesized peptide derived from Human MYO7A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Flow Cytometry
• Clone: 31A12
• Conjugate: Unconjugated
• Gene: MYO7A
• Gene Alias: DFNA11; DFNB2; Hdb; motor protein; MyO VIIa; Myo7; Myo7a; myosin; myosin 7a; myosin VIIA; myosin VIIA (Usher syndrome 1B (autosomal recessive, severe)); myosin-VIIa; Myosin-VIIa motor domain; MYOVIIA; MYU7A; nmf371; NSRD2; polka; sh1; sh-1; shaker 1; unconventional myosin-VIIa; USH1B
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 4647
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid