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MyoD Antibody (MYOD1/2075R), DyLight 680, Novus Biologicals™
SDP

Catalog No. NB009085 Shop All R&D Systems Products
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NB009085 0.1 mL
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Catalog No. NB009085 Supplier Novus Biologicals Supplier No. NBP275772FR
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Description

Rabbit Monoclonal Antibody

MyoD Monoclonal specifically detects MyoD in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen MyoD
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone MYOD1/2075R
Conjugate DyLight 680
Dilution Immunohistochemistry, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
Gene Symbols MYOD1
Host Species Rabbit
Immunogen Recombinant human full-length MyoD protein (Uniprot: P15172 )
Purification Method Protein A purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
Primary or Secondary Primary
Test Specificity Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG
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