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Invitrogen™ MYOD Monoclonal Antibody (1C8)
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Catalog No. PIMA515694
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PIMA515694 100 μL
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Catalog No. PIMA515694 Supplier Invitrogen™ Supplier No. MA515694
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Description

Mouse Monoclonal Antibody

MA5-15694 targets MYOD1 in indirect ELISA, WB applications and shows reactivity with Human samples. The MA5-15694 immunogen is purified recombinant fragment of human MYOD1 expressed in E. Coli. MA5-15694 detects MYOD1 which has a predicted molecular weight of approximately 34kDa.

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOD
Applications ELISA, Western Blot
Classification Monoclonal
Clone 1C8
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene MYOD1
Gene Accession No. P15172
Gene Alias AI503393; bHLHc1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; myoblast determination protein 1 homolog; Myod; MYOD1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; myogenic factor 3; PUM; unnamed protein product
Gene Symbols MYOD1
Host Species Mouse
Immunogen Purified recombinant fragment of human MYOD1 expressed in E. Coli.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4654
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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