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MyoD Monoclonal Antibody (5F11), Active Motif™
SDP

Catalog No. 501993021
Encompass
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50-199-3021 100 μg
50-199-3022 10 μg
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Catalog No. 50-199-3021 Supplier Active Motif Supplier No. 39991
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Description

Rat Monoclonal Antibody

The Myogenic determination gene (MyoD) was first identified by the virtue of its ability to convert embryonic mouse fibroblast cells to muscle cells. It was subsequently shown that forced expression of MyoD (human homolog is myf 3) gene in a wide variety of normal and neoplastic cells could either convert the cells to muscle cells or activate a set of the otherwise transcriptionally inactive muscle-specific genes in these cells. The regulatory domain of the MyoD gene product lies within a 70 amino acid region and comprises a basic DNA binding motif and a helix-loop-helix (HLH) dimerization motif. Subsequent studies identified three other genes whose products shared sequence homology for the basic HLH domain of MyoD. These are; myf5, myogenin (human homolog is myf4) and myf6 (also known as MRF4 and herculin).

Specifications

Antigen MyoD
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Monoclonal
Clone 5F11
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene MYOD1
Gene Accession No. P10085, P15172
Gene Alias AI503393; BHLHC1; Class C basic helix-loop-helix protein 1; CMD1; MYF3; Myf-3; Myoblast determination protein 1; Myoblast determination protein 1 homolog; MYOD; Myod1; Myod-1; MYOD1 homolog; myogenic differentiation 1; myogenic factor 1; Myogenic factor 3; PUM
Gene Symbols MYOD1
Host Species Rat
Immunogen This MyoD antibody was raised against a recombinant protein corresponding to full-length mouse MyoD.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17927, 4654
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a
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