MyoD Antibody (MYOD1/2075R), DyLight 755, Novus Biologicals™

Rabbit Monoclonal Antibody

Supplier:  Novus Biologicals NBP275772IR

Catalog No. NB009088

Description

MyoD Monoclonal specifically detects MyoD in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

• Antigen: MyoD
• Classification: Monoclonal
• Conjugate: DyLight 755
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: MYOD1
• Immunogen: Recombinant human full-length MyoD protein (Uniprot: P15172 )
• Quantity: 0.1 mL
• Research Discipline: Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
• Test Specificity: Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
• Content And Storage: Store at 4°C in the dark.

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
• Clone: MYOD1/2075R
• Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
• Gene Alias: bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG