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Invitrogen™ MYOF Polyclonal Antibody
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Catalog No. PIPA590458
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100 μL
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PIPA590458 100 μL
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Catalog No. PIPA590458 Supplier Invitrogen™ Supplier No. PA590458
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MLRVIVESAS NIPKTKFGKP DPIVSVIFKD EKKKTKKVDN ELNPVWNEIL EFDLRGIPLD FSSSLGIIVK DFETIGQNKL IGTATVALKD LTGDQSRSLP YKLISLLNEK GQDTGATIDL VIGYDPPSAP HPNDLSGPSV PGMGGDGEED EGDEDRLDNA VRGPGPKGPV GTVSEAQLAR RLTKVKNSRR; Positive Samples: U-251MG, A-549, HeLa, NIH/3T3; Cellular Location: Cell membrane, Cytoplasmic vesicle membrane, Nucleus membrane, Single-pass type II membrane protein.

Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOF
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Myof
Gene Accession No. Q69ZN7, Q9NZM1
Gene Alias 2310004N10Rik; 2310051D19Rik; E030042N20Rik; FER1L3; fer-1-like 3, myoferlin; fer-1-like family member 3; fer-1-like protein 3; KIAA1207; Myof; Myoferlin; RGD1564216; zgc:63504; zgc:63504 protein
Gene Symbols Myof
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human MYOF (NP_0384791).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 226101, 26509
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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