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MyoGEF Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501987988
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100 μL
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50-198-7988 100 μL
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Catalog No. 50-198-7988 Supplier Bioss Supplier No. BS7756R
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Description

Rabbit Polyclonal Antibody

PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

Specifications

Antigen MyoGEF
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene PLEKHG6
Gene Accession No. Q3KR16
Gene Alias MyoGEF; myosin II interacting GEF; myosin interacting guanine nucleotide exchange factor; Myosin-interacting guanine nucleotide exchange factor; PH domain-containing family G member 6; pleckstrin homology and RhoGEF domain containing G6; pleckstrin homology domain containing, family G (with RhoGef domain) member 6; Pleckstrin homology domain-containing family G member 6; PLEKHG6
Gene Symbols PLEKHG6
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human MyoGEF.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55200
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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