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Invitrogen™ MYOM1 Polyclonal Antibody
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Catalog No. PIPA553143
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PIPA553143 100 μL
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Catalog No. PIPA553143 Supplier Invitrogen™ Supplier No. PA553143
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: GITDTEEERI KEAAAYIAQR NLLASEEGIT TPKQSTASKQ TTASKQSTAS KQSTASKQST ASRQSTASRQ SVVSKQATSA LQQEETSEKK SRKVVIREKA ERLSLRKTLE ETETYHAKLN EDHLLHAPEF IIKPRSHTVW EKENV Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 81%.

The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD (myomesin 1) and 165 kD (myomesin 2). This protein, myomesin 1, like myomesin 2, titin, and other myofibrillar proteins contains structural modules with strong homology to either fibronectin type III (motif I) or immunoglobulin C2 (motif II) domains. Myomesin 1 and myomesin 2 each have a unique N-terminal region followed by 12 modules of motif I or motif II, in the arrangement II-II-I-I-I-I-I-II-II-II-II-II. The two proteins share 50% sequence identity in this repeat-containing region. The head structure formed by these 2 proteins on one end of the titin string extends into the center of the M band. The integrating structure of the sarcomere arises from muscle-specific members of the superfamily of immunoglobulin-like proteins. Alternatively spliced transcript variants encoding different isoforms have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOM1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Myom1
Gene Accession No. P52179
Gene Alias 190 kDa connectin-associated protein; 190 kDa titin-associated protein; D430047A17Rik; EH-myomesin; MYOM1; myomesin (M-protein) 1 (190kD); myomesin 1; myomesin 1 (skelemin) 185kDa; myomesin 1, 185kDa; myomesin family member 1; Myomesin-1; skelemin
Gene Symbols Myom1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MYOM1. Recombinant protein control fragment (Product #RP-90711).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8736
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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