Invitrogen™ Myosin Skeletal Muscle Monoclonal Antibody (414)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135718

Catalog No. 01-672-024

Description

Mab 414 reacts with myosin-containing elements in most cell types. Antigen localization: cytoplasm In Western blot experiments the antibody reacts with a 75kD part of the heavy chain (epitope location on a myosin-common sitechain), no reaction with light chains. It is not reactive with alpha-cardiac myosin. Positive control: muscle, myofibrils (chicken).

Myosin is a major contractile protein which converts chemical energy into mechanical energy through the hydrolysis of ATP. Myosin is a hexameric protein composed of a pair of myosin heavy chains (MYH) and two pairs of nonidentical light chains. Myosin heavy chains are encoded by a multigene family. In mammals at least 10 different myosin heavy chain (MYH) isoforms have been described from striated, smooth, and nonmuscle cells. These isoforms show expression that is spatially and temporally regulated during development.

Specifications

• Antigen: Myosin Skeletal Muscle
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: tissue culture supernatant with 0.09% sodium azide
• Gene Accession No.: P12882, P13538, Q28641, Q29RW1, Q5SX39, Q5SX40, Q9UKX2, Q9Y623
• Gene Symbols: Myh1, MYH1E, MYH2, MYH4
• Immunogen: Chicken skeletal muscle cell preparation.
• Regulatory Status: RUO
• Gene ID (Entrez): 100009054, 100009548, 100125991, 17879, 17882, 17884, 287408, 360543, 427788, 4619, 4620, 4622, 691644
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 414
• Conjugate: Unconjugated
• Gene: Myh1
• Gene Alias: 2A myosin heavy chain; 2B myosin heavy chain; A530084A17Rik; AI506973; epididymis luminal protein 71; fast 2a myosin heavy chain; fast myosin heavy chain; fast myosin heavy chain 2X; HEL71; IBM3; IId; IId/x; inclusion body myopathy 3, autosomal dominant; MdMs; MGC133384; MHC; MHC2A; MHC2B; MHC2X/D; MHC-2X/D; Minimsc; Minmus; MM; MYH1; MYH2; MYH2A; MYH2B; MYH-2B; Myh4; MYHa; MYHas8; MYHC; MyHC-2A; MyHC-2b; MYHC-2d; MyHC-2x; MyHC-2X/D; MyHC-IIA; MyHC-IIb; MyHC-IId/x; MYHC-IIX; MyHC-IIx/d; MYHSA1; MYHSA2; Myhsf; Myhs-f; Myhsf1; Myhs-f1; Myhsf2; Myhs-f2; myosin heavy chain; myosin heavy chain 1; Myosin heavy chain 2; myosin heavy chain 2a; Myosin heavy chain 2b; myosin heavy chain 2d; myosin heavy chain 2X; Myosin heavy chain 4; myosin heavy chain IIa; Myosin heavy chain IIb; myosin heavy chain IIx/d; myosin heavy chain isoform 2b; myosin heavy chain isoform fast type; myosin heavy chain type IIb; myosin heavy chain type IIx; myosin heavy chain, skeletal muscle; myosin heavy chain, skeletal muscle, adult 1; Myosin heavy chain, skeletal muscle, adult 2; myosin heavy chain, skeletal muscle, fetal; Myosin heavy chain, skeletal muscle, juvenile; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy chain 2, skeletal muscle, adult; myosin, heavy chain 4, skeletal muscle; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin, heavy polypeptide 2, skeletal muscle, adult; myosin, heavy polypeptide 4, skeletal muscle; myosin-1; Myosin-2; myosin-4; MYPOP; skeletal muscle myosin heavy chain II-a; type 2X myosin heavy chain; type IIA myosin heavy chain; unnamed protein product
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Rabbit, Chicken
• Product Type: Antibody
• Isotype: IgM