Invitrogen™ Myotilin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA558082

Catalog No. PIPA558082

Description

Immunogen sequence: ACVAKNRAGE ATFTVQLDVL AKEHKRAPMF IYKPQSKKVL EGDSVKLECQ ISAIPPPKLF WKRNNEMVQF NTDRISLYQD NTGRVTLLIK DVNKKDAG Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 95%.

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: Myotilin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYOT
• Gene Alias: 5530402I04Rik; 57 kDa cytoskeletal protein; LGMD1; LGMD1A; MFM3; Myo; Myofibrillar titin-like Ig domains protein; MYOT; Myotilin; titan-like protein; titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin); Ttid; TTOD
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 9499
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UBF9
• Gene Symbols: MYOT
• Immunogen: Recombinant protein corresponding to Human Myotilin. Recombinant protein control fragment (Product #RP-102782).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov