Invitrogen™ Myotilin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110008

Catalog No. PIPA5110008

Description

Immunogen sequence: RPNQTLPAPK QLRVRPTFSK YLALNGKGLN VKQAFNPEGE FQRLAAQSGL YESEEL.

This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specifications

• Antigen: Myotilin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MYOT
• Gene Alias: 5530402I04Rik; 57 kDa cytoskeletal protein; LGMD1; LGMD1A; MFM3; Myo; Myofibrillar titin-like Ig domains protein; MYOT; Myotilin; titan-like protein; titin immunoglobulin domain protein; titin immunoglobulin domain protein (myotilin); Ttid; TTOD
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 291605, 58916, 9499
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 0.47 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9JIF9, Q9UBF9
• Gene Symbols: MYOT
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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