Invitrogen™ Myotrophin Monoclonal Antibody (1F3)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA524520

Catalog No. PIMA524520

Description

Peptide Sequence: MCDKEFMWAL KNGGLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ.

The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6. 4 kDa tumor antigen that is associated with myeloproliferative disease.

Specifications

• Antigen: Myotrophin
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: MTPN
• Gene Alias: 5033418D15Rik; GCDP; Granule cell differentiation protein; growth factor; Mtpn; Myotrophin; protein V-1; stimulates myocyte growth; V1; V-1; V-1 protein
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 136319
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Clone: 1F3
• Formulation: PBS with no preservative; pH 7.4
• Gene Accession No.: P58546
• Gene Symbols: MTPN
• Immunogen: MTPN (AAH28093, 1 a.a. ~ 118 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a κ