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Invitrogen™ MYOZ2 Monoclonal Antibody (1D4)
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Catalog No. PIMA524461
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100 μg
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Catalog No. Quantity
PIMA524461 100 μg
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Catalog No. PIMA524461 Supplier Invitrogen™ Supplier No. MA524461
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Description

Mouse Monoclonal Antibody

Peptide Sequence: MLSHNTMMKQ RKQQATAIMK EVHGNDVDGM DLGKRVSIPR DIMLEELSHL SNRGARLFKM RQRRSDKYTF ENFQYQSRAQ INHSIAMQNG KVDGSNLEGG SQQAPLTPPN TPDPRSPPNP DNIAPGYSGP LKEIPPEKFN TTAVPKYYQS PWEQAISNDP ELLEALYPKL FKPEGKAELP DYRSFNRVAT PFGGFEKASR MVKFKVPDFE LLLLTDPRFM SFVNPLSGRR SFNRTPKGWI SENIPIVITT EPTDDTTVPE SEDL.

The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOZ2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 1D4
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.4
Gene MYOZ2
Gene Accession No. Q9NPC6
Gene Alias 1110012I24Rik; C4orf5; calcineurin-binding protein calsarcin-1; calsarcin-1; CMH16; CS-1; Fatz-2; FATZ-related protein 2; muscle-specific protein; myoz2; myozenin 2; myozenin-2; myozenin-like 2; Myozl2
Gene Symbols MYOZ2
Host Species Mouse
Immunogen MYOZ2 (AAH05195, 1 a.a. ~ 264 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51778
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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