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Invitrogen™ MYOZ2 Polyclonal Antibody
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Catalog No. PIPA557390
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100 μL
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PIPA557390 100 μL
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Catalog No. PIPA557390 Supplier Invitrogen™ Supplier No. PA557390
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: LEELSHLSNR GARLFKMRQR RSDKYTFENF QYQSRAQINH SIAMQNGKVD GSNLEGGSQQ APLTPPNTPD PR Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 85%.

The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to α-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYOZ2
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MYOZ2
Gene Accession No. Q9NPC6
Gene Alias 1110012I24Rik; C4orf5; calcineurin-binding protein calsarcin-1; calsarcin-1; CMH16; CS-1; Fatz-2; FATZ-related protein 2; muscle-specific protein; myoz2; myozenin 2; myozenin-2; myozenin-like 2; Myozl2
Gene Symbols MYOZ2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MYOZ2. Recombinant protein control fragment (Product #RP-96741).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51778
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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