Myozenin 2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7169	150 μL

Catalog No. 50-172-7169 Supplier Proteintech Group Inc Supplier No. 114501AP150UL

Description

Rabbit Polyclonal Antibody

Proteintech's Myozenin-2 antibody 11450-1-AP was raised against full-length protein of human origin and is able to detect a band of approximately 34 kDa in Western blotting.

The calcineurin-binding protein Myozenin 2, also designated calsarcin-1, is a member of the calsarcin protein family. Calcineurin is a calcium- and calmodulin-dependent protein phosphatase that is involved in controlling the slow fiber gene expression in skeletal muscle and hypertrophy of cardiac muscle. The calsarcins are sarcomeric proteins that couple calcineurin and muscle activity. In cardiac and skeletal muscle cells, Myozenin 2 binds calcineurin to alpha-actinin at the Z-line of the sarcomere. During embryogenesis, Myozenin 1 and 2 are expressed in developing muscle. The Myozenin 2 gene maps to chromosome 4q and is expressed specifically in adult cardiac and slow-twitch skeletal muscle, while Myozenin 1 is only detected in fast skeletal muscle.

Specifications

• Antigen: Myozenin 2
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.13 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: MYOZ2
• Gene Accession No.: Q9JJW5, Q9NPC6
• Gene Alias: C4orf5, Calsarcin-1, FATZ related protein 2, MYOZ2, Myozenin 2
• Gene Symbols: Myoz2
• Host Species: Rabbit
• Immunogen: Myozenin 2 Fusion Protein Ag2008
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 295426, 51778, 59006
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG