Invitrogen™ MYSM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578629

Catalog No. PIPA578629

Description

Positive Control: HeLa, HepG2 Predicted Reactivity: Mouse (86%), Chicken (81%), Bovine (88%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Specifications

• Antigen: MYSM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mysm1
• Gene Alias: 2ADUB; 2A-DUB; C130067A03Rik; C530050H10Rik; Histone H2A deubiquitinase MYSM1; KIAA1915; Myb like, SWIRM and MPN domains 1; myb-like, SWIRM and MPN domain-containing protein 1; myb-like, SWIRM and MPN domains 1; Mysm1; RGD1311787; RP4-592A1.1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114803
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q5VVJ2
• Gene Symbols: Mysm1
• Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human MYSM1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG