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Invitrogen™ MYSM1 Polyclonal Antibody
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Catalog No. PIPA591929
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100 μL
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PIPA591929 100 μL
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Catalog No. PIPA591929 Supplier Invitrogen™ Supplier No. PA591929
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Description

Rabbit Polyclonal Antibody

Positive Samples: U-87MG, A-431, HepG2, HeLa, Jurkat, Mouse brain, Rat brain; Cellular Location: Nucleus Immunogen sequence: SYRLPYKFEV QQMLEEPQWG LVFEKTRWII EKYRLSHSSV PMDKIFRRDS DLTCLQKLLE CMRKTLSKVT NCFMAEEFLT EIENLFLSNY KSNQENGVTE EN.

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYSM1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.47 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Mysm1
Gene Accession No. Q5VVJ2, Q69Z66
Gene Alias 2ADUB; 2A-DUB; C130067A03Rik; C530050H10Rik; Histone H2A deubiquitinase MYSM1; KIAA1915; Myb like, SWIRM and MPN domains 1; myb-like, SWIRM and MPN domain-containing protein 1; myb-like, SWIRM and MPN domains 1; Mysm1; RGD1311787; RP4-592A1.1
Gene Symbols Mysm1
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 720-821 of human MYSM1 (NP_0010789561).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114803, 298247, 320713
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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