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Invitrogen™ MYSM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102696

Catalog No. PIPA5102696


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Description

Description

Antibody detects endogenous levels of total MYSM1.

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

MYSM1
Polyclonal
Unconjugated
Mysm1
2ADUB; 2A-DUB; C130067A03Rik; C530050H10Rik; Histone H2A deubiquitinase MYSM1; KIAA1915; Myb like, SWIRM and MPN domains 1; myb-like, SWIRM and MPN domain-containing protein 1; myb-like, SWIRM and MPN domains 1; Mysm1; RGD1311787; RP4-592A1.1
Rabbit
Affinity chromatography
RUO
114803, 298247, 320713
-20°C
Liquid
Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q5VVJ2, Q69Z66
Mysm1
A synthesized peptide derived from human MYSM1(Accession Q5VVJ2), corresponding to amino acid residues A645-Y695.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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