Invitrogen™ MYSM1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5102696

Catalog No. PIPA5102696

Description

Antibody detects endogenous levels of total MYSM1.

Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.

Specifications

• Antigen: MYSM1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Mysm1
• Gene Alias: 2ADUB; 2A-DUB; C130067A03Rik; C530050H10Rik; Histone H2A deubiquitinase MYSM1; KIAA1915; Myb like, SWIRM and MPN domains 1; myb-like, SWIRM and MPN domain-containing protein 1; myb-like, SWIRM and MPN domains 1; Mysm1; RGD1311787; RP4-592A1.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 114803, 298247, 320713
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q5VVJ2, Q69Z66
• Gene Symbols: Mysm1
• Immunogen: A synthesized peptide derived from human MYSM1(Accession Q5VVJ2), corresponding to amino acid residues A645-Y695.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov