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Invitrogen™ MYZAP Polyclonal Antibody
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Catalog No. PIPA558946
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100 μL
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PIPA558946 100 μL
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Catalog No. PIPA558946 Supplier Invitrogen™ Supplier No. PA558946
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TVPPESPVPE QCEKKIERKE QLLDLSNGEP TRKLPQGVVY GVVRRSDQNQ QKEMVVYGWS TSQLKEEMNY IKDVRATLEK VRKRMYGDYD EM Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.

MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MYZAP
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MYZAP
Gene Accession No. P0CAP1
Gene Alias AA407270; AV006038; gcom; GCOM1; Gcom2; Gm640; GRINL1A; GRINL1A combined protein; GRINL1A complex locus 1; GRINL1A complex locus protein 1; GRINL1A complex locus upstream; GRINL1A upstream protein; Grinl1a7; Gup; myocardial intercalated disc protein; myocardial zonula adherens protein; myocardium-enriched ZO1-associated protein; myocardium-enriched zonula adherens protein; myocardium-enriched zonula occludens-1-associated protein; myozap; Myzap; MYZAP-POLR2M
Gene Symbols MYZAP
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MYZAP. Recombinant protein control fragment (Product #RP-98067).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100820829
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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