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Invitrogen™ MZB1 Polyclonal Antibody
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Catalog No. PIPA560493
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PIPA560493 100 μL
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Catalog No. PIPA560493 Supplier Invitrogen™ Supplier No. PA560493
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: YGVREVDQVK RLTGPGLSEG PEPSISVMVT GGPWPTRLSR TCLHYLGEFG EDQIYEAHQQ GRGALEALLC GGPQGACSEK VSATR Highest antigen sequence identity to the following orthologs: Mouse - 73%, Rat - 74%.

MZB1 associates with immunoglobulin M (IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity. Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation.; Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MZB1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MZB1
Gene Accession No. Q8WU39
Gene Alias caspase-2 binding protein; HSPC190; marginal zone B and B1 cell specific protein; marginal zone B and B1 cell-specific protein; marginal zone B- and B1-cell-specific protein; MEDA7; MEDA-7; Mesenteric estrogen-dependent adipose 7; mesenteric oestrogen-dependent adipose gene- 7; MGC29506; MZB1; PACAP; pERp1; plasma cell-induced ER protein 1; plasma cell-induced resident endoplasmic reticulum protein; Plasma cell-induced resident ER protein; proapoptotic caspase adapter protein; proapoptotic caspase adaptor protein
Gene Symbols MZB1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MZB1. Recombinant protein control fragment (Product #RP-100226).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51237
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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